I love the idea of a "long term" computer, but the thing that terrifies me about the Amiga (or the C64, or the Atari 400/800, or the Apple IIe) is how dependent they are on custom no-longer-produced chips. Sure, those chips might last a long time, but there's only going to be fewer and fewer of them over time.

At least the 6502 is still being commercially produced, and most TTL 74* chips too, so the original Apple II should easily last 50 years... but I/O is kind of a pain and the lack of full ASCII keyboard and display is crippling.